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 | Seeking Glue-free and Plastic-free closure of paper packaging |
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We are looking for a technology to seal paper packaging materials (paper only with no plastic coating) without using traditional glues or any other additive. For a sustainable packaging application, we're looking for a technology to seal or crimp kraft paper without using glue or plastic coating applied on the paper. Ideally, we want to seal 100% untreated paper without adding any other chemicals. Our preferred solution would be a folding of the packaging material |
 | Seeking Recycling technologies for biodegradable films |
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We are looking for solutions to convert bio-based packaging back to starting materials or other high-value added chemicals (no fuels). |
| | Seeking Recyclable Closure for Paper Beverage Bottles |
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We are seeking technologies for a re-closable fiber-based closure for a paper beverage bottle that can be recycled in the paper stream. |
 | Improving stem cell culture using carnivorous plants |
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Mesenchymal Stem Cells (MSCs) are multipotent precursor cells with the unique capacity to self-renew, proliferation and transformation into specialized cells present in many body tissues, such as muscle, adipose tissue, fibroblasts, cartilage, tendons, and nervous tissue. They are also characterized by the ability to affect the immune system by secretion of compounds that support the immune response directed among others against bacteria and parasites. They have properties enabling the secretion of chemical compounds that stimulate the formation of new blood vessels. All these attributes make them applicable in regenerative medicine, transplantology and in the treatment of many diseases. The umbilical cord blood and Wharton’s jelly MSCs are the sources from which MSCs are obtained. Due to the small amount of MSCs in the starting material, it is necessary to lead in vitro cultures to obtain sufficient numbers of cells that can be administered to the patient. Methods of isolation and culture of mesenchymal stem cells, including the growth medium, play a crucial role in obtaining the appropriate biological material that guarantees therapeutic success. Therefore, continuous improvement of procedures for isolating and in vitro culturing of MSCs is extremely important. The subject of the offer is a method of culturing mesenchymal stem cells using secretions from carnivorous plants, which increase cell adherence and proliferation, counteract their transformation into specialized cells, therefore, they longer maintain their pluripotency. |
 | New method to improve treatment of atrial fibrillation |
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Researchers from the CNIC and HCSC have developed a system to guide ablation procedures in a patient-specific way in complex cases of persistent atrial fibrillation, identifying these key regions to be treated with great precision and specificity. Furthermore, it does not require additional equipment or consumables, but only software that could be implemented within any conventional electroanatomical browser, so it would not make current pulmonary vein isolation procedures more expensive, with the advantage of being able to perform patient-specific ablation in complex cases. |
 | Nitroxoline for prevention and treatment of coronavirus disease |
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University of Ljubljana has repurposed Nitroxolin for the prevention and treatment of diseases caused by coronaviruses, in particular SARS-CoV-2. A significant advantage of nitroxoline over other candidate drugs for the treatment of covid-19 (repurposing drugs – amantadine, teicoplanin) is that the mechanism of action on the target has been extensively investigated. Our process can additionally generate a variety of compounds with improved antiviral activity. |
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